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The major disadvantages of this use are cocaine’s potential for cardiovascular toxicity, glaucoma, and pupil dilation. Some ENT specialists occasionally use cocaine within the practice when performing procedures such as nasal cauterization.
Even when used this way, some of the used cocaine may be absorbed through the oral or nasal mucosa and give systemic effects.
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Cocaine is a powerful nervous system stimulant. Its effects can last from fifteen or thirty minutes to an hour. The duration of cocaine’s effects depends on the amount taken and the route of administration.  Cocaine can be in the form of fine white powder, bitter to the taste. When inhaled or injected, it causes a numbing effect.
Cocaine use leads to increases in alertness, feelings of well-being and euphoria, increased energy and motor activity, and increased feelings of competence and sexuality